Related Clues:

• Trying
• Difficult
• Lab work
• Laborious
• Challenging
• Examining
• Screening
• Difficult trial
• It's often spoken into microphones
• '1, 2, 3' lead-in
• It may be very trying and very painful at last
• Trying and painful in the end
• Trying to cause pain at last
• How trying so to cause pain at last
• See 21