Related Clues:

• Thorns in one's side
• Archenemies
• Causes of distress
• Blights
• Sources of distress
• Sources of harm
• Misery causes
• Sources of frustration
• Causes of destruction
• Downfalls
• Sources of ruin
• Sunlight and garlic, to vampires
• 'Musical fruit,' if you've 106-Across
• Causes of ruination
• Causes of unhappiness