Related Clues:
- New York's most populous upstate county
- Lake near Niagara Falls
- Eastern Woodlands tribe
- Lake ___ College, in 16-Across
- Sandusky's county
- One of a great quintet
- The shallowest Great Lake
- ___-Lackawanna Railroad
- Strange-sounding city?
- Home to Commodore Perry's ship Niagara
- Superior neighbor
- Cleveland Indian
- Buffalo shore
- Lake or tribe
- War of 1812 port