Related Clues:

• Modern lead-in to a disappointed remark
• Nonstandard ''Anyway . . .''
• Lead-in to some bad news
• 'So, that's disappointing,' online
• 'Eh, what can you do?!'
• Modern slang for "Alas ..."
• 'So much for that!'
• "Alas," informally
• "I guess that's that"
• Slangy lead-in to "What can you do?"