Related Clues:

• Expression of resignation
• Locker room interview cliche #2
• An inflammation, but which one? Let's move on (2,2,4,2,2)
• 'That's life' ... and a summing-up of 20-, 29- and 47-Across
• "That's life" ... and a summing-up of 20-, 29- and 47-Across
• Circular saw?
• 'We'll just have to adapt,' redundantly