Related Clues:

• Drives up the wall
• Frosts
• Exasperates
• Grates on
• Grinds down
• Ruffles feathers
• Annoys over time
• Proves troublesome
• Plagues
• Aggravates
• Gets one's goat
• Gets under one's skin
• Patronizes, as a restaurant
• Really bothers
• Ruffles one's feathers