Related Clues:

• Give a shot, perhaps
• Make calm
• Staid
• Make chill
• Far from jumpy
• Cool and calm
• Amicable
• Anesthetize, say
• Give Valium to, e.g.
• Free from worry
• Even-tempered
• Calm and composed
• Hit with a tranquilizer dart
• Prim
• Calm and dignified