Related Clues:

• Infuriation
• Heat
• Bad news from a credit card company
• Rile
• Bile
• Ruffle one's feathers
• Get one's dander up
• It must be managed
• Repudiation
• Cause to see red
• Subject of a management course?
• Sorehead's emotion
• It may need some management
• One might take classes to manage it
• Negation