Related Clues:

• With one's back to the wall
• Suffering adversity, Ian opts out
• Behind the eightball
• Stranded at home at midday raised heads
• Awkwardly situated (colloq.)
• Breaking-point, since trapped up the creek
• A piston worked with difficulty
• One backed leading medical establishment having problems
• A piston worked up against it
• Having difficulty, one not managing to limit something poisonous
• Having difficulty at home representing corporation
• Having trouble travelling to Spain
• Up against it, adult inside points out
• Facing a problem
• Facing difficulties in moving to Spain