Related Clues:

• Annoy greatly
• Annoy no end
• Really bug
• Gnaw into
• Really get to
• Arouse bitterness
• Embitter
• Get on one's nerves
• Persistently irritate
• Fester in one's mind
• Continue to irritate
• Bother big-time
• Cause irritation
• Get on the nerves of
• Cause lasting resentment