Related Clues:

• With the least delay
• First to arrive
• As quickly as possible
• At the earliest opportunity
• Soonest
• As early as possible
• Happening first
• Original or most previous
• Very first in a sterile manner
• Nearest the start of a time period
• Nearest the beginning in time
• The first to arrive - to get the worm?
• 'Least said, ... mended (7)'
• Sort of most noble, perhaps, but never of late
• Maybe the most noble, but never of late