Related Clues:

• Reliever's target
• Baby brother, often
• Annoyance, so to speak
• Partner of suffering
• Result of punishment
• Pill
• Grimace inducer
• Bothersome task
• Major hassle
• 'No ___, no gain'
• It might be in the neck
• ___ in the ass
• It can be chronic or shooting
• Suffering partner?
• Major inconvenience