Related Clues:

• Cry of despair (and a hint to solving 17-, 26-, 38- and 52-Across
• Does it sound as if it's all one? On the contrary!
• 'There's no hope!'
• 'We're done for'
• Words of total despair
• 'We're doomed!'
• 2013 Robert Redford movie
• “We’re done for!”
• Lament of defeat
• "I'm sunk!"
• "It's hopeless!"