Related Clues:
- Pelee Island's lake
- Lake that feeds Niagara Falls
- See 42-Across
- Western New York county
- One of the Iroquois
- 'Phaedra' playwright
- Canal with a mule named Sal
- Gannon University locale
- New York's ___ Canal
- Cuyahoga's outlet
- Enemies of the Iroquois
- New York and ___ Railroad, started in 1832
- See 5-Down
- Toledo's lake
- Canal zone?