Related Clues:

• Depressed
• Sick and tired
• Sickened
• Mad as hops
• Disgruntled
• Totally annoyed
• Exasperated
• Angry, and not going to take it anymore
• Ready to walk
• Sick and tired of it all
• Out of patience
• Unhappy
• Sick of it all
• Angry and impatient
• At the end of one's rope