Related Clues:

• I-79 terminus
• Presque Isle locale
• View from Sandusky
• Welland Canal outlet
• Southernmost Great Lake
• Buffalo's lake
• See 39-Down
• New York county
• See 45-Down
• 'Holy cow!'
• Astronaut Carpenter
• Cleveland's lake
• I-79's northern terminus
• Northwest Pennsylvania city
• Foe of the Iroquois