Related Clues:

• In a guinea pig it results in tooth loss
• Hollow (in tooth)
• Destination for a filling!
• Hole (in a tooth?)
• Empty area
• Rodent eats it in hole
• This hole has a guinea-pig sitting outside it
• In about six years, time to make a little space
• Exactly what's needed in rodent's hole
• Internal void
• Hole in tooth?
• The thing nipped by rodent, creating a hole
• Guinea pig fed it in space
• Opening to be filled
• Hole in tooth