Related Clues:

• Exterminator's target
• Termite, e.g.
• Destructive insect
• Vexatious sort
• Irksome sort
• Troublesome insect
• Cause of a rash
• Obnoxious person
• 10 Across or 49 Across
• Flea, e.g.
• Sitter's challenge
• Pain in the butt
• Mole, e.g.
• Annoying type
• Hassle