Related Clues:

• Blowing one's top
• Plenty mad
• Composite
• Cross-species
• Ticked off, and then some
• Ranting and raving
• Needing to cool down, maybe
•     Steamed
• Very mad
• Good and steamed
• Mad as can be
• More than a little upset
• Itching for a fight
• Like many a letter to the editor
• Really displeased