Possible Clues:

• Abandon Edward with the yeast
• Unlike matzo
• Unlike bread on Passover, and like four of the five sets of circled letters in this puzzle
• One will arise and go now to Edward
• Abandon Edward for the rise
• Abandon Edward if he's given one a rise
• Leave it to Edward to get a rise this way
• Give Edward notice, even if he gave you a rise
• Abandon Edward to get a rise out of him
• Like soda crackers