Possible Clues:

• Source of annoyance
• Institute writing with bluster over city centre will only inflame things
• Source of continual annoyance
• Pain in the neck
• Rita is at the heart of this nuisance
• A source of continual annoyance
• One runs twice with it, to worker's annoyance
• Dripping faucet, perhaps
• I speak angrily about king, and it becomes a distraction
• Annoying factor