Possible Clues:

• What Germans call ''Deutsche Dogge''
• Large smooth-haired dog
• Marmaduke, e.g
• Beastly one in Hamlet?
• Dog in stormy tea garden
• One who barks out ''Hamlet'' perhaps
• Scooby-Doo, e.g.
• Very large dog of a breed originating in Germany
• Stoop beneath fireplace, picking up dog
• The return of 27 across for Hamlet?