Possible Clues:

• Figured (out), in slang
• ___-up (on strong medication)
• Calculated, with ''out''
• Nobbled, taking up shell
• Oversedated, maybe
• Administered a narcotic
• Subject to removal from the horse race
• 'Nature had it all -- out for me to be the Belle of Hicks Corners' (P. G. Wodehouse, A Damsel in Distress)
• After party passed fool hiding, having taken drugs
• Worked (out)