Possible Clues:

• Fundamental shifting in cargo
• Live pipes at play, I see
• A top-level Internet dom­ain, one I start to consider as a living thing
• Produced by natural means
• Natural? Close, but no cigar, unfortunately
• In cargo (anag.)
• The sort of crop I can grow out West, perhaps
• Made from living matter
• Oscar racing badly? That's natural
• Naturally produced, or artificially, by grain co.