Possible Clues:

• The cause of sicknmess and any more on the continent
• EU member from the beginning some supported
• European federal republic
• Country for example returning first of refugees -- then a great number
• Bad setting
• Rival team that could make me angry
• What may be sneezed into the air — and then some land
• Country associated with 38-/40-/41-Across
• European country that borders nine others
• Note principal features of European referendum: a good deal for the country