Possible Clues:

• Drive insane
• Upset journalist reverting to type?
• Madden monarch who's in endless peril
• If you pressed the bell in the river it would send you dotty
• Called to find, indeed, unfinished. Make you mad
• Disorder and risk reduced when Queen is involved
• Drive mad queen into jeopardy, almost
• Drive to distraction
• Put out order: 'En garde!'
• Send over the edge