Possible Clues:

• Breaker for ship of the desert?
• Take on ex-Foreign Secretary, showing tipping point in exasperation?
• Endure growths coming up? Something ultimately exasperating
• The final act rearranged 11-across's
• Back-breaker?
• Ultimate provocation
• The limit starts to need adjustment in principle
• This the camel found unbearable
• Cause for exclaiming "I've had enough!"
• Repeatedly street artist breaks rule -- that finally does it