Possible Clues:

• With 10-Down, 36-Across-designed museum
• Genre with a Hall of Fame in Cleveland ... or what can follow the respective halves of 17-, 33- and 40-Across
• What's eaten at the seaside with bread that's old-fashioned now?
• Music category
• 'Let's do this!'
• Bill Haley's music
• Blend of rhythm-and-blues and country-and-western music
• '50s listening
• With 60-Across, institution in which 19-, 25- and 37-Across are (thus far) the only three women ever to be inducted twice
• Chuck Berry's thing