Possible Clues:

• Reform please, after right's decline...
• Slip back, as into illness
• Fall back - about to expire
• Pearl's upset having minimal energy - setback in health terms
• Become sick again
• Slide back into former condition as of illness (7)
• Fall back into former condition, being pleaser
• Get sick again
• Setback upsets comparatively poor bridge opponents
• Genuine software said to be a setback