Possible Clues:

• 'Why you little...' target, often
• "Why you little..." target, often
• SF subway system, for short
• Big Krusty fan
• ''Simpsons'' son
• Homer Simpson's boy
• Cartoon boy who can be described by an anagram of his name
• Perpetual 10-year-old of TV
• One of Homer's greatest creations?
• Former baseball commissioner Giamatti